This loss was preceded by the fall of Manchester City in the trap of drawing 3 times in a row against Chelsea, Tottenham and Liverpool, now behind the leaders Arsenal by 6 points.
It is the first time that Manchester City have failed to win 4 consecutive games since April 2017, in Guardiola's first season at the helm of the coaching staff of "Citizens".
Guardiola admitted that he needed to find solutions to get out of the crisis, saying: "We are 6 points behind Arsenal and we would have liked to be in the lead, but we drew 3 times and then lost tonight."
"In recent years we have managed to find a way to win but we have suffered a little bit and we have to find a solution."
"It is my responsibility to find this solution, to change the dynamic in order to win. You have to admit when the opponent is better than you."
"Aston Villa played better than us. In the first half we didn't go well in the ball despite possession, and in the second half things improved and we created some chances but we couldn't find the finishing touch in the good times".
City's four defeats this season came in the absence of influential Spanish midfielder Rodri, who missed the Aston Villa clash with cards as did former Villa winger Jack Grealish.
Overall, Manchester City are unbeaten in their last 43 games in which Rodri has participated, with Guardiola commenting: "Rodri is an important player in the team of course, but when he's not with us, we have to find a way to win in his absence."
It is noteworthy that City missed in the last period to the services of his Belgian playmaker Kevin De Bruyne due to injury, and his return to the stadiums is approaching.