Research, the results of which were published in BMJ Medicine, demonstrate the dependence of the amount of fat in the body on the consumption of caffeine.

With a high level of caffeine in the blood, fat does not accumulate in the body and the risk of developing type 2 diabetes is reduced.

Previous studies have shown that daily consumption of 3-5 cups of coffee can reduce the risk of developing heart disease and type 2 diabetes.

On average, a cup of coffee contains 70-150 mg of caffeine.

But these results are rather observational, not quantitative in nature.

To clarify such studies and establish cause-and-effect relationships between coffee consumption and obesity, the researchers used Mendelian randomization.

Mendelian randomization is a technique that uses genetic variants, in this case blood caffeine levels, to obtain genetic evidence of caffeine's effect on weight and type 2 diabetes risk.

There have been six long-term studies examining the role of two common genetic variants, CYP1A2 and AHR, in nearly 10,000 people.

These genes are responsible for the rate of metabolism of caffeine in the body.

According to the results of the study, it was found that

higher genetically predicted levels of caffeine in the blood are associated with lower weight (body mass index), less body fat, and a lower risk of developing type 2 diabetes.

It was found that among all the factors that influence weight loss and reducing the risk of developing type 2 diabetes, the share of caffeine consumption was 43%. 

As the researchers note, caffeine accelerates metabolism, increases fat burning and reduces appetite, they explain.

Daily consumption of 100 mg of caffeine increases energy expenditure by 100 calories per day, which, as a result, leads to weight loss and reduces the risk of obesity.

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