Even though it looks like the situation of the Covid-19 outbreak

around the world will continue to decline

But really, the corona virus has not been defeated because of the latest reports that

which is a strain that is currently

Outbreaks in Singapore, Hong Kong and many European countries.

In addition to mutating into a new species.

It also has the ability to spread faster than the original species.

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from the Faculty of Medicine

Chulalongkorn University

Regarding the COVID-19 strain BQ.1.1 and XBB, which are the latest strains to mutate from the original strain of this virus, the latest data from Gerstung M, University of Heidelberg, Germany, identified the coronavirus coded that BQ.1.1 and XBB are two species that are likely to be crowding in a new wave of epidemics that are emerging in the world.

The spreading performance of the BQ.1.1 virus strain was about 12% faster than BA.5 on average (range from 10% in Belgium to 15% in Germany), while XBB was faster than BA.5. Over 20% in Singapore (but around 7% in Denmark and 13% in the US).

Dr. Thira said

In principle, it is expected that the factors that strongly influence the nature of the outbreak in each country.

It's not just about the virus strain.

But it will be an overview of the prevention and control of that country.

Since the surveillance system is concentrated or lax.

“Reporting the real situation to people in society in detail and timely or as open as they want to open

Open when you want to open up people's harm and risk perceptions as a result of policies and measures of the responsible government agencies that focus on protecting and appreciating people's health and life," said Dr Thira.

The most important thing is

Caring for the health of each person and each family to protect themselves during their daily life.

especially living consciously, prudently, with caution and wearing masks correctly

This will greatly reduce the risk.

such information

It seems to be consistent with the information on the part of virologists such as

, director of the Animal Health and Management Innovation Research Group.

The National Center for Genetic Engineering and Biotechnology (Biotech) National Science and Technology Development Agency (NSTDA) states that XBB and BQ.1.1 are two virus strains that are being discussed a lot right now.

And is likely to replace BA.5, which owns the same area in the coming winter. XBB has an outbreak in Asia, while BQ.1.1 is a strain in Europe.

and the United States

Dr Anan said the two viruses had the same variation on most spikes.

But there are some positions that can make a difference.

The mutational sites on XBB are greater than BQ.1.1, which some sites are believed to have resulted in immune antibodies previously generated from the vaccine.

Or infected from other species in nature to be caught poorly, resulting in XBB better escape the immune system infecting human cells.

Director of Animal Health and Management Innovation Research Group

It further states that BQ.1.1 has a location L452R, which XBB does not have. This location is the signature of the Delta virus and BA.5 allows the virus to bind more tightly to the ACE2 receptor protein on the cell surface. BQ.1.1 may be inferior to XBB, but if given the opportunity to bind to ACE2, this virus has a better chance of infecting cells than XBB.

“It is noteworthy that the very important location of a Delta strain, P681R, allows the delta virus to grow well and achieve massive cellular fusion.

It hasn't happened in the Omicron family of viruses, where both BQ.1.1 and XBB viruses choose a change at this location.

It's a variation found in the Alpha family, and there's no clear explanation as to why P681R is only found in Delta, but unstable in Omikron spikes.

This is something that nature has chosen,” Dr. Anan explains.

Along with saying that now BQ.1.1 may change itself more like XBB or XBB may bring L452R in to make itself better infect cells like BQ.1.1 or if the 2 virus species coexist, it may occur. Can mix between XBB-BQ.1.1 as well

As a result, the released virus tends to increase the immune system's ability to escape.

and increased infection

The severity of the spike is also indistinguishable from the changes in the spike protein.

The response from the host must be looked at as an estimator.

As virologists are monitoring mutations and their ability to bind in cells and escape immunity to the latest strain of the coronavirus.

Singapore's Ministry of Health (MOH) has issued a public warning that

The XBB strain of covid may be a serious epidemic.

And as many as 15,000 people may be infected per day by mid-November.