Magic mushrooms, the future cures depression, depression

stubborn doctor

26 Jun 2022 5:20 a.m.

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The doctor had learned about it in the previous article on the topic of staghorn mushrooms, magic mushrooms, psychedelic plants.

Become a medical miracle (29 November 2020 Thai Rath Health Fun)

By telling about the information published in a scientific journal (Science) until your study.

This was a tightly controlled study.

and no side effects or complications were found.

And the good results can be continued for up to four weeks after treatment.

and more than half are in a condition called remission.

Disease or depression, depression is something that cannot be overlooked.

and had a huge impact.

not only myself

but also the people around you and your family and society

in western countries

which should include in Thailand

Depression medication will be prescribed.

already a lot of depression

and increasing enormously, especially during the covid crisis

but in spite of this

Many antidepressants have little effect.

As summarized in the various reports from the articles that will be discussed below.

and reflects the treatment model.

who want to aim at different levels and positions

Depressed patients have a pessimistic view of the world.

lack of flexibility

both in the process of thinking

and a tendency to cling to the conventional cognitive states (attractor states).

A research study using the image processing process of the brain.

(Neuroimaging) in this depressive disorder

It is rooted in the fact that the patient's brain has a default mode network (DMN), which is the functional network of the human brain.

when faced with external conditions

but will reiterate and re-circulate with their own feelings

and affect the brain network

In terms of operations (Executive network-EN) and work priorities and problems (Salience network-SN), which is the heart of normal life.

which humans must have the ability to switch off - on (automatic switching) during self-care, but must be open

in order to rhyme with what is happening around

This form of action involves the serotonin 2 A (5 HT-2A) receptor subtype, and this itself is an important proteomic agent that we like to call psychedelic drug psilocybin. Psychedelic psychedelic wandering the universe

Even this genre, dubbed psychedelic rock in the mid-1960s, was influenced to become progressive.

EXPERIMENT ROCK Art Rock Artists such as Frank Zappa Jimi Hendrix

There are even Beatles songs Sgt Pepper's lonely hearts club band and magical mystery tour and The Doors Rolling Stones on Their Satanic majesties request.

Such receptors or receptors that bind to dope are densely distributed in the cortex and are linked in a chain.

The network is a map between the DMN EN and SN.

During the past 15 years, there have been at least six clinical trials of psilocybin.

And every report shows an effective treatment.

in alleviating and suppressing the symptoms of depression and depression in resistant patients

to standard treatment

and in many reports are comparative

Therapeutic effect between standard drugs

The serotonin reuptake inhibitor (SSRI) by psilocybin was more effective.

A study reported in the journal Nature, April 11, 2022, uses psilocybin derived from drunkard mushrooms for the treatment of depression from Imperial College and Kings College London's Center for Neuroimaging Sciences that studies the brain.

both in terms of structure and function and merger processing

working of parts

in disease conditions

Functional neuroimaging-fMRI suggests that psilocybin is activated through this receptor binding process.

and resulting in a sufficiency adjustment of the use of energy landscape

In the wider and more stable brain (flatter global energy landscape) it makes the neurons

There was a lot more discussion on the different sections.

independently

In standard medicine, neither SSRI nor escitalopram had any such effect.

in this study

It included nearly 60 participants with depression, depression, and drug resistance. The first was an open-label study using 10 and 25 mg of psilocybin seven days apart.

The patients resisted to the current standard treatment.

And brain activity pattern studies with fMRI were performed on the first day and one day after the 25 mg dose, and the severity of depression was recorded using Beck's depression inventory measure.

the second study

It is a form that the donor and recipient are not aware of.

A double-blind phase II randomized controlled trial of the standard drug escitalopram was compared with Psilocybin and patients with major depressive disorder, in the first group receiving psilocybin at doses of 2×25 mg three weeks apart.

Six weeks were followed by placebo, and another group received 2×1 mg of Psilo cybin three weeks apart, followed by six weeks with 10 to 20 mg of escitalop ram, as appropriate.

The fMRI was performed on the first day and three weeks after the second dose of psilocybin.

in both studies

The effect of relieving depression with Psilocybin is rapid and long-lasting.

in relation to work

Connected to the brain…by people with better symptoms.

It is linked to the functions of different parts of the brain.

clearly happened

and not during

treatment only

It still has a long-term effect for at least three weeks.

and which will be followed up in the long term

The nature of the ability to open the connection to these different parts of the brain.

They are clearly different from the effects of the drugs currently in use.

And it seems to suggest that psilocybin is more effective because the drug's mechanism of action is more specific in the brain.

in the form of a network

and is a major cause of depression, depression and a more efficient brain function.

and more flexible

by reducing negative patterns of thinking

associated with depression, depression

The report's senior principal investigator

is the professor

Carhart-Harris

also gave an interview that

The mechanism by which psychedelic drugs work is likely to respond.

Answers to other related diseases such as anorexia, a state of starvation

and may be severe until death or even addiction

In this final conclusion

Although the results obtained from the drunken mushrooms

It will be like opening a door to understand how the brain works.

distorted from the original

and resulting in life-threatening conditions or diseases

and can be used as a drug

but at present

treatment in this form

Still need to use the substance that is prepared.

in a constant, appropriate amount as well as controlled

Follow up with a doctor as well.

stubborn doctor

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