Dr. Zhengzong Wei pointed out that COVID-19 can cause autoimmune diseases, such as ankylosing spondylitis, lupus erythematosus, and rheumatoid arthritis.

(Photo by reporter Cai Shuyuan)

[Reporter Cai Shuyuan/Taichung Report] Infection with Wuhan pneumonia will increase the risk of autoimmune diseases!

The Affiliated Hospital of Sun Yat-Sen Medical University and the Kaohsiung Veterans General team cooperated with domestic and foreign big data research, and found that the disease rate was 3% half a year after the diagnosis, which was three times that of uninfected people, and ankylosing spondylitis, lupus erythematosus, rheumatoid arthritis The research was published in "Electronic Clinical Medicine", a sub-journal of the top journal "The Lancet", in February this year.

Wei Zhengzong, vice president of the Affiliated Hospital of Sun Yat-sen Medical University and a doctor of allergy and immunology rheumatology, pointed out that the reason for the increased risk of autoimmune diseases after diagnosis may be the activation of the immune response after infection with the new coronavirus, resulting in a cytokine storm, or viral antigens and autoantigens The structure is similar, leading to cross-reaction, attacking one's own tissue, and inducing autoimmune diseases.

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The study used the global electronic medical records database TriNetX, included a total of 3.8 million PCR-tested cases from January 2020 to December 2021, analyzed 900,000 confirmed cases and 2.9 million control cases, followed up for 180 days, and found confirmed cases for half a year The cumulative incidence of autoimmune diseases after the disease is 3%, which is about three times that of uninfected people.

Wei Zhengzong said that studies have shown that the longer the time after diagnosis, the higher the risk of suffering from autoimmune diseases, among which ankylosing spondylitis (3.21 times), mixed connective tissue disease (3.14 times), systemic lupus erythematosus ( 2.99 times), rheumatoid arthritis (2.98 times), psoriasis (2.98 times), xerosis (2.62 times), vasculitis and polymyositis (1.96 times) are the most common, the study also found that young and middle-aged groups and There are more women, and people with comorbidities and abnormal living habits are more likely to suffer from it.

Wei Zhengzong said that the symptoms of the new coronavirus will disappear after recovery, but the virus will remain in the body for a long time. In addition, it is a new virus, and the immune response of the human body is also more intense, especially for patients with autoimmune diseases and acquired disorders. It is easy to get immune disorders and induce immune diseases, and there is no significant difference in the probability of suffering from mild and severe cases of lung cancer according to race and race. It is recommended that after diagnosis, you should adjust your work and rest as soon as possible, and do a good job in eating and living habits, so that the immune system can return to normal and the body and mind are in balance.

Wei Zhengzong reminded that if long-term joint pain, skin rash, unexplained hair loss, fever, oral ulcers, etc. occur after the diagnosis and recovery, you should seek medical examination as soon as possible.

Wei Zhengzong added that the research on the Wuhan pneumonia patients suffering from autoimmune diseases is also the study of the infection of new coronavirus and autoimmune diseases with the largest number of samples in history. The age, gender, race, socioeconomic status, life style and basic The disease characteristics are similar, and the research results are more accurate.

Dr. Wei Zhengzong reminded that if long-term joint pain, skin rash, unexplained hair loss, fever, oral ulcers, etc. occur after the diagnosis and recovery, you should seek medical examination as soon as possible.

(Photo by reporter Cai Shuyuan)

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keywords

  • living habit

  • rheumatoid arthritis

  • ankylosing spondylitis

  • lupus erythematosus

  • autoimmune disease

  • Wuhan Pneumonia (Novel Coronavirus Disease, COVID-19)

  • acquired disorder

  • immune disorder

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