Ou Hanwen said that when the metabolic rate of histamine in the body is far lower than the rate of accumulation, pseudoallergies will occur, but in essence the immune system does not participate in it. This phenomenon is called histamine intolerance; the picture shows the situation.

(picture taken from freepik)

[Health Channel/Comprehensive Report] Frequent allergic symptoms such as runny nose and sneezing may not necessarily be true allergies, but may be histamine intolerance.

Physicians pointed out that the symptoms of histamine intolerance are similar to allergies, which are caused by abnormal metabolism of histamine in the body, which can cause false allergies in the body, such as nasal congestion, sneezing, itchy skin, urticaria, etc., but can be detected through blood and feces to test.

Dr. Ou Hanwen, a physician from Han's Integrated Functional Medicine Center, posted on the Facebook fan page "Dr. Ou Hanwen Functional Medicine" and his personal website that when it comes to histamine, many people intuitively associate it with allergic reactions. Allergy symptoms such as runny nose, stuffy nose or skin rash or wheezing are part of the body's immune response.

Please read on...

Ou Hanwen mentioned that histamine not only plays an important role in the immune response, but when the metabolic rate of histamine in the body is far lower than the rate of accumulation, pseudoallergies will occur, and the body will have an allergic reaction, but in essence the immune system does not not involved, a phenomenon known as histamine intolerance.

The human body's histamine can be roughly divided into two sources, one is secreted by mast cells in immune cells, which is related to allergic reactions as we know it, and the other is ingested through diet.

Ou Hanwen said that the body of most healthy people has the ability to quickly decompose the histamine ingested from the diet, because the intestine will secrete an enzyme diamine oxidase (DAO) that can decompose histamine. , even if the body can normally produce DAO, but its activity is low, so if you eat foods that contain more histamine in your diet, foods that stimulate histamine secretion or inhibit metabolism, your body may lose its ability to metabolize in time. Amine concentrations become high, producing an allergic-like reaction.

Common Histamine Intolerance Symptoms

●Respiratory tract:

runny nose, rhinitis, nasal congestion, sneezing, dyspnea.

●Gastrointestinal tract:

flatulence, diarrhea, abdominal pain, constipation, nausea, vomiting.

● Cardiovascular:

rapid heartbeat.

●Skin:

itching, hives, swelling, flushing.

●Reproductive system:

dysmenorrhea.

●Nervous system:

migraine, dizziness, fatigue.

Ou Hanwen explained that the symptoms of histamine intolerance are diverse and vary from person to person. In addition, the symptoms are somewhat similar to allergies, so most of the time it is not easy to judge whether it is histamine intolerance based on the symptoms.

However, blood test can be used to evaluate the activity of DAO enzyme in the body to confirm whether the body's ability to decompose histamine is good. At the same time, it can also be used to detect the concentration of histamine in stool to confirm whether there is a problem of histamine intolerance.

Ways to improve histamine intolerance

●Insufficient DAO activity:

It is usually related to gene mutation and cannot be cured, but the congenital deficiency can be improved by supplementing DAO enzyme.

●Dietary intake:

It is recommended to adopt a low-histamine diet. There are many details to pay attention to in this diet, but the general principle is that fresh and unprocessed foods have relatively low histamine content; improperly preserved, highly processed and fermented foods have high histamine content .

●Intestinal health:

When the intestinal flora is out of balance, more histamine will be secreted. At the same time, the excessive proliferation of small intestinal flora, mycotoxins, and candida hyperplasia may aggravate the problem of histamine intolerance. Therefore, if there is Intestinal dysfunction, it is recommended to give priority to treatment.

●Nutrient deficiency:

The DAO enzyme that metabolizes histamine requires the participation of nutrients such as vitamin B6, vitamin C, and copper. Therefore, when the dietary intake is insufficient, the metabolism of histamine will also be affected.

●Stress relief and adequate sleep:

Long-term high pressure, lack of sleep, or abnormal work and rest will all have negative effects. Therefore, if there are problems in this area, doctors should give individual treatment strategies for each case.

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keywords

  • allergy

  • Histamine

  • immunity

  • gut health

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