The Food and Drug Administration reminds that excessive scratching will cause skin damage and worsen inflammation. Although the use of antihistamines and steroids can quickly relieve discomfort, follow-up attention should be paid to whether there is any excessive use of drugs; the picture shows the situation. Characters are irrelevant to this article.

(The picture is taken from photoAC)

[Health Channel/Comprehensive Report] The climate in Taiwan is unstable, which can easily worsen the symptoms of patients with atopic dermatitis. In addition, people often make mistakes or overuse medications, so they have not been improved; in this regard, the Food and Drug Administration stated that atopic dermatitis The treatment of inflammation is divided into 3 stages. In the initial stage, oral and topical drugs should be used intermittently; in the worsening stage, oral or injectable steroid drugs should be used; in the severe stage, oral or injectable immunomodulator drugs should be used to reduce allergic reactions.

According to the Food and Drug Administration, atopic dermatitis is an allergic chronic skin disease, accompanied by thickening of the epidermis, forming skin lesions of itchy eczema.

When itching occurs, it is easy to scratch the skin tissue and affect the barrier function of the skin, allowing external irritants and allergens to enter the body and trigger an inflammatory response.

If the histamine released by the inflammatory reaction further causes itching, the patient scratches again, resulting in a vicious circle.

Please read on...

According to the Food and Drug Administration, the treatment of atopic dermatitis is mainly divided into 3 stages:

1. Initial stage:

More moisturizers should be given, and antihistamine drugs and steroid drugs should be used intermittently.

Moisturizers can be divided into lotions, gels, creams and ointments. In hot and humid summers, lotions can be applied, while in dry and cold winters, creams or ointments can be used instead.

Common antihistamine drugs include Diphenylpyraline HCL for smearing and Cetirizine for oral administration; steroid drugs Betamethasone Dipropionate or Fluocinolone Acetonide for smearing.

The Food and Drug Administration reminds that before applying moisturizers or topical medicines, hands must be washed first, and the affected area should also be cleaned before applying.

2. Deterioration stage:

Combined with oral or injectable steroid drugs, such as Prednisolone for short-term use, and topical immunomodulator drugs, such as 0.1% Tacrolimus ointment (Ointment) for adults and 0.03% Tacrolimus ointment for children, 1% Pimecrolimus milk Cream (Cream), and the newer topical PDE-4 inhibitor drug 2% Crisaborole ointment.

3. Severe stage:

Use oral or injected immunomodulator drugs to reduce allergic reactions. Commonly used drugs such as Cyclosporine, Methotrexate, Azathioprine, and Mycophenolate; there are also injectable biologics Dupilumab; and oral targeted small molecule drugs, such as Abrocitinib, Baricitinib and Upadacitinib.

3 major treatment improvements for atopic dermatitis

●Skin moisturizer: use it when the skin is rough and dry, at least 2 times a day.

An oily ointment with no or little water content, such as petroleum jelly, can be used, and topical urea can also reduce skin moisture loss.

●Skin antipruritic agent: reduce itching and avoid infection.

It is recommended to use an anti-itch ointment without added cooling agents. Oral antihistamines can be used for severe itching, but attention should be paid to side effects and drowsiness.

●Topical steroids: they are the main treatment, but it is not recommended for the public to purchase them for long-term use.

Topical steroids only need to be applied to the affected area to avoid affecting normal skin tissue.

Itching of the skin is one of the most disturbing symptoms of atopic dermatitis, especially the change of seasons will make patients feel very much.

The Food and Drug Administration reminds that excessive scratching can cause skin damage and worsen inflammation.

The use of antihistamines and steroids can quickly relieve discomfort, but follow-up attention should be paid to whether there is any excessive use of drugs.

The Food and Drug Administration recommends that if you have any problems related to atopic dermatitis, you should immediately consult a physician or a pharmacist in a nearby pharmacy to find the most suitable treatment and disposal method.

More importantly, you should follow the doctor's advice, and cooperate with the doctor, pharmacist or pharmacist's instructions, and complete the medication under the correct treatment period and dosage. Don't stop taking the medicine because you are worried about side effects or thinking that your symptoms have improved slightly.

In addition, you should read the instruction manual carefully before taking the medicine, pay attention to the storage method and expiration date, so as to ensure the safety of your medicine and properly deal with the discomfort caused by atopic dermatitis.

Reprinted from Issue 899 of the Food and Drug Safety Weekly Report of the Food and Drug Administration of the Ministry of Defense and Welfare

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